
Science Simplified – What Treatment Should I Start With?
What is the best first treatment for follicular lymphoma? We break down current standards, new research from ASH 2025, and what it could mean for your care.
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What is the best first treatment for follicular lymphoma? We break down current standards, new research from ASH 2025, and what it could mean for your care.

On 9th March came the announcement that tazemetostat (Tazverik) is being voluntarily withdrawn worldwide. Ipsen, the company that markets tazemetostat, made this decision after new safety findings emerged from the ongoing SYMPHONY 1 clinical trial, which indicated a possible increased risk of secondary blood cancers when the drug was used in a specific combination regimen (lenalidomide and rituximab, also referred to as R2).

NICE has approved epcoritamab (Tepkinly) on the NHS for adults in England, Wales and Northern Ireland with relapsed or refractory follicular lymphoma after two prior treatments. The decision introduces a new bispecific antibody therapy option for patients with limited treatment choices.